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Pim-1 kinase inhibitor 8
CAS No. 916038-47-6
Pim-1 kinase inhibitor 8 ( —— )
产品货号. M37329 CAS No. 916038-47-6
Pim-1 kinase inhibitor 8 (compound 12) 是 Pim-1 kinase 的有效抑制剂，其 IC50 为 14.3 nM。Pim-1 kinase inhibitor 8 对 MCF-7 和 HepG2 细胞具有较强的细胞毒性，其 IC50 分别为 0.5 和 5.27 μM。Pim-1 kinase inhibitor 8 可用于乳腺癌研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥736 | 有现货 |
|
| 5MG | ￥1122 | 有现货 |
|
| 10MG | ￥1793 | 有现货 |
|
| 25MG | ￥3496 | 有现货 |
|
| 50MG | ￥5615 | 有现货 |
|
| 100MG | ￥8645 | 有现货 |
|
| 500MG | ￥17519 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Pim-1 kinase inhibitor 8
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Pim-1 kinase inhibitor 8 (compound 12) 是 Pim-1 kinase 的有效抑制剂，其 IC50 为 14.3 nM。Pim-1 kinase inhibitor 8 对 MCF-7 和 HepG2 细胞具有较强的细胞毒性，其 IC50 分别为 0.5 和 5.27 μM。Pim-1 kinase inhibitor 8 可用于乳腺癌研究。
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产品描述Pim-1 kinase inhibitor 8 (compound 12) is a potent inhibitor of Pim-1 kinase with an IC50 of 14.3 nM. Pim-1 kinase inhibitor 8 has potent cytotoxicity against MCF-7 and HepG2 cells with IC50s of 0.5 and 5.27 μM, respectively. Pim-1 kinase inhibitor 8 can used in study breast cancer.
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体外实验——
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体内实验——
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同义词——
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通路Angiogenesis
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靶点PKC
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受体PKC | Pim
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研究领域——
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适应症——
化学信息
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CAS Number916038-47-6
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分子量275.3
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分子式C14H17N3O3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 125 mg/mL (454.05 mM; 超声助溶 )
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SMILESN#CC1=C(N=C(C=C1C)C)OCC(=O)N2CCOCC2
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Shaban SM, et al. Design and Synthesis of Novel Pyridine-Based Compounds as Potential PIM-1 Kinase Inhibitors, Apoptosis, and Autophagy Inducers Targeting MCF-7 Cell Lines: In Vitro and In Vivo Studies. ACS Omega. 2023 Nov 27;8(49):46922-46933.?
产品手册
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